Drug Information

Drug General Information
Drug ID
D0P4SR
Former ID
DNC005796
Drug Name
2-(4-Hydroxy-phenyl)-1-p-tolyl-3H-inden-5-ol
Drug Type
Small molecular drug
Indication Discovery agent Investigative [527738]
Structure
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2D MOL

3D MOL
Formula
C22H18O2
Canonical SMILES
CC1=CC=C(C=C1)C2=C(CC3=C2C=CC(=C3)O)C4=CC=C(C=C4)O
InChI
1S/C22H18O2/c1-14-2-4-16(5-3-14)22-20-11-10-19(24)12-17(20)13-21(22)15-6-8-18(23)9-7-15/h2-12,23-24H,13H2,1H3
InChIKey
YIFNILRPNDYIBP-UHFFFAOYSA-N
PubChem Compound ID
11716633
Target and Pathway
Target(s) Estrogen receptor beta Target Info Inhibitor [527738]
KEGG Pathway Estrogen signaling pathway
Prolactin signaling pathway
Pathway Interaction Database Plasma membrane estrogen receptor signaling
Validated nuclear estrogen receptor beta network
Validated nuclear estrogen receptor alpha network
Reactome Nuclear Receptor transcription pathway
WikiPathways SIDS Susceptibility Pathways
Ovarian Infertility Genes
Integrated Pancreatic Cancer Pathway
Nuclear Receptors
References
Ref 527738J Med Chem. 2005 Sep 22;48(19):5989-6003.Differential response of estrogen receptor subtypes to 1,3-diarylindene and 2,3-diarylindene ligands.
Ref 527738J Med Chem. 2005 Sep 22;48(19):5989-6003.Differential response of estrogen receptor subtypes to 1,3-diarylindene and 2,3-diarylindene ligands.

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