TTD | Drug: D0P6KN

Drug General Information
Drug ID	D0P6KN
Former ID	DIB020062
Drug Name	INS48823
Synonyms	INS-48823; INS 48823
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[539097]
Structure		Download 2D MOL
Formula	C26H31N4O20P3
InChI	InChI=1S/C26H31N4O20P3/c31-16-6-8-29(25(35)27-16)23-20(34)19(33)14(45-23)11-43-51(37,38)49-53(41,42)50-52(39,40)44-12-15-21-22(24(46-15)30-9-7-17(32)28-26(30)36)48-18(47-21)10-13-4-2-1-3-5-13/h1-9,14-15,18-24,33-34H,10-12H2,(H,37,38)(H,39,40)(H,41,42)(H,27,31,35)(H,28,32,36)/t14-,15+,18?,19-,20-,21+,22+,23-,24+/m0/s1
InChIKey	FIZCPSOYGRAJHH-LAJHJGSGSA-N
PubChem Compound ID	44457307
PubChem Substance ID	103762260, 135650401, 160850701
Target and Pathway
Target(s)	P2Y purinoceptor 6	Target Info	Agonist	[528028]
KEGG Pathway	Neuroactive ligand-receptor interaction
Reactome	G alpha (q) signalling events
Reactome	P2Y receptors
WikiPathways	Nucleotide GPCRs
	GPCRs, Class A Rhodopsin-like
	Gastrin-CREB signalling pathway via PKC and MAPK
	GPCR ligand binding
	GPCR downstream signaling
References
Ref 539097	(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 1746).
Ref 528028	P2 receptors activated by uracil nucleotides--an update. Curr Med Chem. 2006;13(3):289-312.

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Drug Information