Drug Information
Drug General Information | |||||
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Drug ID |
D0PI4H
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Former ID |
DIB021163
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Drug Name |
VPC12249
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Synonyms |
VPC 12249; VPC-12249
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Drug Type |
Small molecular drug
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Indication | Discovery agent | Investigative | [539926] | ||
Structure |
Download2D MOL |
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Formula |
C34H52NO6P
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InChI |
InChI=1S/C34H52NO6P/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-19-22-34(36)35-32(29-41-42(37,38)39)27-30-23-25-33(26-24-30)40-28-31-20-17-16-18-21-31/h9-10,16-18,20-21,23-26,32H,2-8,11-15,19,22,27-29H2,1H3,(H,35,36)(H2,37,38,39)/b10-9-/t32-/m1/s1
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InChIKey |
NJLPYJKKKSBCSK-MJPIYRIWSA-N
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PubChem Compound ID | |||||
PubChem Substance ID | |||||
Target and Pathway | |||||
Target(s) | Lysophosphatidate-3 receptor | Target Info | Antagonist | [526205] | |
Sphingosine-1-phosphate receptor-3 | Target Info | Agonist | [528528] | ||
Lysophosphatidic acid receptor Edg-2 | Target Info | Antagonist | [526205] | ||
NetPath Pathway | TGF_beta_Receptor Signaling Pathway | ||||
References | |||||
Ref 526205 | Activity of 2-substituted lysophosphatidic acid (LPA) analogs at LPA receptors: discovery of a LPA1/LPA3 receptor antagonist. Mol Pharmacol. 2001 Dec;60(6):1173-80. | ||||
Ref 528528 | Synthesis and biological evaluation of gamma-aminophosphonates as potent, subtype-selective sphingosine 1-phosphate receptor agonists and antagonists. Bioorg Med Chem. 2007 Jan 15;15(2):663-77. Epub2006 Nov 1. |
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