Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0Q3KF
|
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| Former ID |
DNC008842
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| Drug Name |
4'-((2-butylbenzofuran-3-yl)methyl)biphenyl-4-ol
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| Drug Type |
Small molecular drug
|
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| Indication | Discovery agent | Investigative | [1] | ||
| Structure |
|
Download2D MOL |
|||
| Formula |
C25H24O2
|
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| Canonical SMILES |
CCCCC1=C(C2=CC=CC=C2O1)CC3=CC=C(C=C3)C4=CC=C(C=C4)O
|
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| InChI |
1S/C25H24O2/c1-2-3-7-25-23(22-6-4-5-8-24(22)27-25)17-18-9-11-19(12-10-18)20-13-15-21(26)16-14-20/h4-6,8-16,26H,2-3,7,17H2,1H3
|
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| InChIKey |
AESGURZHBVMCOS-UHFFFAOYSA-N
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| PubChem Compound ID | |||||
| Target and Pathway | |||||
| Target(s) | mRNA of Protein tyrosine phosphatase-1B | Target Info | Inhibitor | [1] | |
| KEGG Pathway | Adherens junction | ||||
| Insulin signaling pathway | |||||
| NetPath Pathway | FSH Signaling Pathway | ||||
| PANTHER Pathway | Cadherin signaling pathway | ||||
| Pathway Interaction Database | Insulin Pathway | ||||
| Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met) | |||||
| Signaling events mediated by PTP1B | |||||
| Calcineurin-regulated NFAT-dependent transcription in lymphocytes | |||||
| Signaling events mediated by TCPTP | |||||
| IGF1 pathway | |||||
| EGF receptor (ErbB1) signaling pathway | |||||
| Posttranslational regulation of adherens junction stability and dissassembly | |||||
| PDGFR-beta signaling pathway | |||||
| N-cadherin signaling events | |||||
| Reactome | Integrin alphaIIb beta3 signaling | ||||
| Regulation of IFNG signaling | |||||
| Regulation of IFNA signaling | |||||
| Growth hormone receptor signaling | |||||
| WikiPathways | Insulin Signaling | ||||
| Growth hormone receptor signaling | |||||
| Leptin signaling pathway | |||||
| Interferon gamma signaling | |||||
| Interferon alpha/beta signaling | |||||
| Integrin alphaIIb beta3 signaling | |||||
| References | |||||
| REF 1 | Bioorg Med Chem. 2009 Apr 1;17(7):2658-72. Epub 2009 Mar 5.Synthesis, activity and molecular modeling of a new series of chromones as low molecular weight protein tyrosine phosphatase inhibitors. | ||||
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