Drug Information

Drug General Information
Drug ID
D0Q5KL
Former ID
DAP000964
Drug Name
Coagulation Factor IX
Indication Haemophilia B; Christmas disease [ICD9: 286.1; ICD10:D67] Approved [533123], [550670]
Therapeutic Class
Anticoagulants
Formula
C2041H3136N558O641S25
CAS Number
CAS 9001-28-9
SuperDrug ATC ID
B02BD04
Target and Pathway
Target(s) Coagulation factor Xa Target Info Activator [536124]
KEGG Pathway Complement and coagulation cascades
PANTHER Pathway Blood coagulation
Pathway Interaction Database Beta2 integrin cell surface interactions
PathWhiz Pathway Coagulation
Reactome Extrinsic Pathway of Fibrin Clot Formation
Intrinsic Pathway of Fibrin Clot Formation
Common Pathway of Fibrin Clot Formation
Gamma-carboxylation of protein precursors
Transport of gamma-carboxylated protein precursors from the endoplasmic reticulum to the Golgi apparatus
Removal of aminoterminal propeptides from gamma-carboxylated proteins
WikiPathways Complement and Coagulation Cascades
Human Complement System
PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
Blood Clotting Cascade
Formation of Fibrin Clot (Clotting Cascade)
References
Ref 5331232014 FDA drug approvals. Nat Rev Drug Discov. 2015 Feb;14(2):77-81.
Ref 550670Drug information of Coagulation Factor IX, 2008. eduDrugs.
Ref 536124Haemophilia B: Christmas disease. Expert Opin Pharmacother. 2005 Aug;6(9):1517-24.

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