Drug Information

Drug General Information
Drug ID
D0Q8LS
Former ID
DNC009556
Drug Name
2-[4-(2-Piperidin-1-ylethyl)phenoxy]benzothiazole
Drug Type
Small molecular drug
Indication Discovery agent Investigative [529569]
Structure
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2D MOL

3D MOL
Formula
C20H22N2OS
Canonical SMILES
C1CCN(CC1)CCC2=CC=C(C=C2)OC3=NC4=CC=CC=C4S3
InChI
1S/C20H22N2OS/c1-4-13-22(14-5-1)15-12-16-8-10-17(11-9-16)23-20-21-18-6-2-3-7-19(18)24-20/h2-3,6-11H,1,4-5,12-15H2
InChIKey
DHHMVJVCMLXZBO-UHFFFAOYSA-N
PubChem Compound ID
11427736
Target and Pathway
Target(s) Potassium voltage-gated channel subfamily H member 2 Target Info Inhibitor [529569]
Leukotriene A-4 hydrolase Target Info Inhibitor [529569]
BioCyc Pathway Leukotriene biosynthesis
KEGG Pathway Arachidonic acid metabolism
Metabolic pathways
PathWhiz Pathway Muscle/Heart ContractionPW000044:Arachidonic Acid Metabolism
Reactome Voltage gated Potassium channels
WikiPathways SIDS Susceptibility Pathways
Hematopoietic Stem Cell Differentiation
Potassium ChannelsWP2650:Arachidonic acid metabolism
Eicosanoid Synthesis
References
Ref 529569J Med Chem. 2008 Jul 24;51(14):4150-69. Epub 2008 Jun 28.Identification of a potent, selective, and orally active leukotriene a4 hydrolase inhibitor with anti-inflammatory activity.
Ref 529569J Med Chem. 2008 Jul 24;51(14):4150-69. Epub 2008 Jun 28.Identification of a potent, selective, and orally active leukotriene a4 hydrolase inhibitor with anti-inflammatory activity.

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