Drug Information
Drug General Information | |||||
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Drug ID |
D0R1CR
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Former ID |
DAP000807
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Drug Name |
L-Phenylalanine
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Synonyms |
Endophenyl; Fenilalanina; Phe; Phenylalanine; Phenylalaninum; Fenilalanina [Spanish]; Phenylalaninum [Latin]; Antibiotic FN 1636; CB 3208; NCI9959; Alpha-Aminohydrocinnamic acid; Beta-Phenylalanine; L-Antibiotic FN 1636; L-PHENYLALININE; N-Formylmelphalan; Phenylalanine (VAN); H-Phe-OH; L-Phenylalanine (JP15); Phenylalanine (USP/INN); Phenylalanine [USAN:INN:JAN]; Beta-Phenyl-L-alanine; N-Formyl-L-sarcolysin; N-Formyl-L-p-sarcolysin; L-PHENYL ALANINE (SEE ALSO 22839-47-0, ASPARTAME; L-3-(p-(Bis(2-chloroethyl)amino)phenyl)-N-formylalanine; L-Phenylalanine, 4-(bis(2-chloroethyl)amino)-N-formyl-(9CI); (2S)-2-amino-3-phenylpropanoic acid; (L)-Phenylalanine; (S)-(-)-Phenylalanine; (S)-2-Amino-3-phenylpropanoic acid; (S)-2-Amino-3-phenylpropionic acid; (S)-Phenylalanine; (S)-alpha-Amino-benzenepropanoic acid; (S)-alpha-Amino-beta-phenylpropionic acid; (S)-alpha-Aminohydrocinnamic acid; 1F9436B3-8B0D-4AC6-A004-4249B0BDA436; 3-Phenyl-L-alanine; 3-Phenylalanine; 3-[4-[bis(2-chloroethyl)amino]phenyl]-2-formamidopropanoic acid
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Drug Type |
Small molecular drug
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Therapeutic Class |
Dietary supplement
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Structure |
Download2D MOL |
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Formula |
C9H11NO2
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InChI |
InChI=1S/C9H11NO2/c10-8(9(11)12)6-7-4-2-1-3-5-7/h1-5,8H,6,10H2,(H,11,12)/t8-/m0/s1
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InChIKey |
COLNVLDHVKWLRT-QMMMGPOBSA-N
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CAS Number |
CAS 63-91-2
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PubChem Compound ID | |||||
PubChem Substance ID |
3379, 584667, 822460, 824902, 832928, 838754, 841094, 3134198, 4252550, 6436530, 7847089, 7889851, 8144203, 8153851, 10531434, 11457628, 11459655, 11528323, 11532528, 14710668, 15219430, 24770335, 24770338, 24770342, 24887247, 24898274, 24898657, 24898971, 24901797, 26651814, 26702643, 26748791, 26748792, 26753740, 29225143, 46391851, 46393329, 46505708, 50107465, 57323218, 57578102, 57652717, 57654567, 57655097, 78164833, 81044023, 81044025, 81044569, 81067307, 81067312
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ChEBI ID |
ChEBI:17295
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Target and Pathway | |||||
Target(s) | Tyrosine 3-monooxygenase | Target Info | Binder | [535693], [536211], [536359] | |
BioCyc Pathway | Catecholamine biosynthesis | ||||
PathWhiz Pathway | Catecholamine Biosynthesis | ||||
References | |||||
Ref 540274 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 3313). | ||||
Ref 550111 | Drug information of L-Alanine, Health Canada, 2008. (drugid: 1025) | ||||
Ref 535693 | In situ and in vitro evidence for DCoH/HNF-1 alpha transcription of tyrosinase in human skin melanocytes. Biochem Biophys Res Commun. 2003 Feb 7;301(2):610-6. | ||||
Ref 536211 | Effect of metals and phenylalanine on the activity of human tryptophan hydroxylase-2: comparison with that on tyrosine hydroxylase activity. Neurosci Lett. 2006 Jul 3;401(3):261-5. Epub 2006 Apr 11. | ||||
Ref 536359 | Selectivity and affinity determinants for ligand binding to the aromatic amino acid hydroxylases. Curr Med Chem. 2007;14(4):455-67. |
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