Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0R2HF
|
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| Former ID |
DNC013517
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| Drug Name |
6-(2-mercaptoacetamido)-N-phenylhexanamide
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent | Investigative | [1] | ||
| Structure |
|
Download2D MOL |
|||
| Formula |
C14H20N2O2S
|
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| Canonical SMILES |
C1=CC=C(C=C1)NC(=O)CCCCCNC(=O)CS
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| InChI |
1S/C14H20N2O2S/c17-13(16-12-7-3-1-4-8-12)9-5-2-6-10-15-14(18)11-19/h1,3-4,7-8,19H,2,5-6,9-11H2,(H,15,18)(H,16,17)
|
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| InChIKey |
ICMLRCZXRBTKLJ-UHFFFAOYSA-N
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| PubChem Compound ID | |||||
| Target and Pathway | |||||
| Target(s) | Histone Deacetylase 8 | Target Info | Inhibitor | [1] | |
| KEGG Pathway | Alcoholism | ||||
| Viral carcinogenesis | |||||
| PANTHER Pathway | Wnt signaling pathway | ||||
| Pathway Interaction Database | Signaling events mediated by HDAC Class I | ||||
| Reactome | NOTCH1 Intracellular Domain Regulates Transcription | ||||
| Constitutive Signaling by NOTCH1 PEST Domain Mutants | |||||
| Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants | |||||
| HDACs deacetylate histones | |||||
| WikiPathways | Integrated Pancreatic Cancer Pathway | ||||
| Neural Crest Differentiation | |||||
| Cell Cycle | |||||
| References | |||||
| REF 1 | J Med Chem. 2008 Mar 27;51(6):1505-29. Epub 2008 Feb 5.Histone deacetylase inhibitors: from bench to clinic. | ||||
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