Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0R2QS
|
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| Former ID |
DNC001008
|
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| Drug Name |
Neplanocin A
|
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| Drug Type |
Small molecular drug
|
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| Indication | Discovery agent | Terminated | [1] | ||
| Structure |
|
Download2D MOL |
|||
| Formula |
C11H13N5O3
|
||||
| Canonical SMILES |
C1=C(C(C(C1N2C=NC3=C2N=CN=C3N)O)O)CO
|
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| InChI |
1S/C11H13N5O3/c12-10-7-11(14-3-13-10)16(4-15-7)6-1-5(2-17)8(18)9(6)19/h1,3-4,6,8-9,17-19H,2H2,(H2,12,13,14)/t6-,8-,9+/m1/s1
|
||||
| InChIKey |
XUGWUUDOWNZAGW-VDAHYXPESA-N
|
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| CAS Number |
CAS 72877-50-0
|
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| PubChem Compound ID | |||||
| PubChem Substance ID | |||||
| Target and Pathway | |||||
| Target(s) | Adenosylhomocysteinase | Target Info | Inhibitor | [2] | |
| BioCyc Pathway | Superpathway of methionine degradation | ||||
| Methionine degradation | |||||
| Cysteine biosynthesis | |||||
| KEGG Pathway | Cysteine and methionine metabolism | ||||
| Metabolic pathways | |||||
| PathWhiz Pathway | Selenoamino Acid Metabolism | ||||
| Betaine Metabolism | |||||
| Methionine Metabolism | |||||
| WikiPathways | Metabolism of amino acids and derivatives | ||||
| Trans-sulfuration and one carbon metabolism | |||||
| One Carbon Metabolism | |||||
| Trans-sulfuration pathway | |||||
| Phase II conjugation | |||||
| Folate Metabolism | |||||
| References | |||||
| REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800001045) | ||||
| REF 2 | Molecular approaches for the treatment of hemorrhagic fever virus infections. Antiviral Res. 1993 Sep;22(1):45-75. | ||||
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