Drug Information

Drug General Information
Drug ID
D0R6PF
Former ID
DIB019502
Drug Name
compound 42
Drug Type
Small molecular drug
Indication Discovery agent Investigative [531890], [541070]
Structure
Download
2D MOL
Formula
C21H24N8O2
InChI
InChI=1S/C21H24N8O2/c1-14(2)19-26-21(27-31-19)28-6-7-29(15(3)12-28)20-24-10-18(11-25-20)30-13-16-4-5-23-9-17(16)8-22/h4-5,9-11,14-15H,6-7,12-13H2,1-3H3/t15-/m0/s1
InChIKey
UNGZTVLHLKAKQE-HNNXBMFYSA-N
PubChem Compound ID
60168163
PubChem Substance ID
144117271, 178102361
Target and Pathway
Target(s) Glucose-dependent insulinotropic receptor Target Info Agonist [531890]
KEGG Pathway cAMP signaling pathway
Insulin secretion
WikiPathways Incretin Synthesis, Secretion, and Inactivation
References
Ref 531890Use of small-molecule crystal structures to address solubility in a novel series of G protein coupled receptor 119 agonists: optimization of a lead and in vivo evaluation. J Med Chem. 2012 Jun 14;55(11):5361-79.
Ref 541070(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 5735).
Ref 531890Use of small-molecule crystal structures to address solubility in a novel series of G protein coupled receptor 119 agonists: optimization of a lead and in vivo evaluation. J Med Chem. 2012 Jun 14;55(11):5361-79.

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