Drug Information

Drug General Information
Drug ID
D0R8YJ
Former ID
DNC006436
Drug Name
N-ethyl-N-methyl-4-(pyridin-3-yl)but-3-yn-1-amine
Drug Type
Small molecular drug
Indication Discovery agent Investigative [527965]
Structure
Download
2D MOL

3D MOL
Formula
C12H16N2
Canonical SMILES
CCN(C)CCC#CC1=CN=CC=C1
InChI
1S/C12H16N2/c1-3-14(2)10-5-4-7-12-8-6-9-13-11-12/h6,8-9,11H,3,5,10H2,1-2H3
InChIKey
DGPGTYZUJIIMAU-UHFFFAOYSA-N
PubChem Compound ID
44366246
Target and Pathway
Target(s) Neuronal acetylcholine receptor protein, beta-2 chain Target Info Inhibitor [527965]
Neuronal acetylcholine receptor protein, alpha-4 chain Target Info Inhibitor [527965]
KEGG Pathway Neuroactive ligand-receptor interaction
Cholinergic synapse
Nicotine addictionhsa04080:Neuroactive ligand-receptor interaction
Nicotine addiction
PANTHER Pathway Nicotinic acetylcholine receptor signaling pathway
Nicotine pharmacodynamics pathwayP00044:Nicotinic acetylcholine receptor signaling pathway
Nicotine pharmacodynamics pathway
Reactome Highly sodium permeable acetylcholine nicotinic receptors
Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
Highly calcium permeable nicotinic acetylcholine receptorsR-HSA-629587:Highly sodium permeable acetylcholine nicotinic receptors
Highly calcium permeable nicotinic acetylcholine receptors
WikiPathways SIDS Susceptibility Pathways
Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell
Nicotine Activity on Dopaminergic NeuronsWP706:SIDS Susceptibility Pathways
Nicotine Activity on Dopaminergic Neurons
References
Ref 527965Bioorg Med Chem Lett. 2006 Apr 1;16(7):2013-6. Epub 2006 Jan 18.Synthesis and analgesic activity of secondary amine analogues of pyridylmethylamine and positional isomeric analogues of ABT-594.
Ref 527965Bioorg Med Chem Lett. 2006 Apr 1;16(7):2013-6. Epub 2006 Jan 18.Synthesis and analgesic activity of secondary amine analogues of pyridylmethylamine and positional isomeric analogues of ABT-594.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.