Drug Information
Drug General Information | |||||
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Drug ID |
D0S0VZ
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Former ID |
DIB000663
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Drug Name |
IDRA-21
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Synonyms |
IDRA-21 analogs; IDRA-5
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Drug Type |
Small molecular drug
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Company |
Fidia-Georgetown Institute for the Neurosciences
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Structure |
Download2D MOL |
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Formula |
C8H9ClN2O2S
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InChI |
InChI=1S/C8H9ClN2O2S/c1-5-10-7-3-2-6(9)4-8(7)14(12,13)11-5/h2-5,10-11H,1H3
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InChIKey |
VZRNTCHTJRLTMU-UHFFFAOYSA-N
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CAS Number |
CAS 22503-72-6
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PubChem Compound ID | |||||
PubChem Substance ID |
3153204, 4725772, 8152331, 14798209, 24896078, 26752113, 29222811, 47211774, 47959889, 57321941, 75096882, 85787797, 91704602, 103277548, 103807507, 104304235, 117464560, 118696386, 126407681, 129550235, 135116603, 135156569, 135156570, 135698080, 137102587, 142978078, 143857868, 162022823, 162227378, 162817920, 178101036, 184590059, 226553987, 241182241, 241375306, 252451275
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Target and Pathway | |||||
Target(s) | Glutamate receptor AMPA subtype | Target Info | Modulator | [527059] | |
NMDA receptor | Target Info | Modulator | [527059] | ||
References | |||||
Ref 467553 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 4219). | ||||
Ref 527059 | IDRA-21, a positive AMPA receptor modulator, inhibits synaptic and extrasynaptic NMDA receptor mediated events in cultured cerebellar granule cells. Neuropharmacology. 2004 Jun;46(8):1105-13. |
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