TTD | Drug: D0S4XR

Drug General Information
Drug ID	D0S4XR
Former ID	DNC009433
Drug Name	1-(3-(benzyloxy)-2-methylphenyl)piperazine
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[530058]
Structure		Download 2D MOL 3D MOL
Formula	C18H22N2O
Canonical SMILES	CC1=C(C=CC=C1OCC2=CC=CC=C2)N3CCNCC3
InChI	1S/C18H22N2O/c1-15-17(20-12-10-19-11-13-20)8-5-9-18(15)21-14-16-6-3-2-4-7-16/h2-9,19H,10-14H2,1H3
InChIKey	LLKMJMQVKKJDAT-UHFFFAOYSA-N
PubChem Compound ID	25263303
Target and Pathway
Target(s)	5-hydroxytryptamine 6 receptor	Target Info	Inhibitor	[530058]
KEGG Pathway	Calcium signaling pathway
	cAMP signaling pathway
	Neuroactive ligand-receptor interaction
	Serotonergic synapse
PANTHER Pathway	Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
PathWhiz Pathway	Excitatory Neural Signalling Through 5-HTR 6 and Serotonin
Reactome	Serotonin receptors
Reactome	G alpha (s) signalling events
WikiPathways	Serotonin Receptor 4/6/7 and NR3C Signaling
	Monoamine GPCRs
	GPCRs, Class A Rhodopsin-like
	GPCR ligand binding
	GPCR downstream signaling
References
Ref 530058	Bioorg Med Chem Lett. 2009 May 1;19(9):2409-12. Epub 2009 Mar 25.Synthesis and SAR of tolylamine 5-HT6 antagonists.
Ref 530058	Bioorg Med Chem Lett. 2009 May 1;19(9):2409-12. Epub 2009 Mar 25.Synthesis and SAR of tolylamine 5-HT6 antagonists.

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Drug Information