TTD | Drug: D0S9XO

Drug General Information
Drug ID	D0S9XO
Former ID	DIB020328
Drug Name	mercaptoacrylate inhibitor of calpain 1
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[543197]
Structure		Download 2D MOL
Formula	C11H8BrNO2S
InChI	InChI=1S/C11H8BrNO2S/c12-7-1-2-9-8(4-7)6(5-13-9)3-10(16)11(14)15/h1-5,13,16H,(H,14,15)/b10-3-
InChIKey	RLEKFRNXGFHPHZ-KMKOMSMNSA-N
PubChem Compound ID	90668184
PubChem Substance ID	242616608, 252166771
Target and Pathway
Target(s)	Calpain	Target Info	Inhibitor	[543595]
KEGG Pathway	Protein processing in endoplasmic reticulum
	Apoptosis
	Alzheimer's disease
Reactome	Degradation of the extracellular matrix
WikiPathways	Focal Adhesion
	Integrated Pancreatic Cancer Pathway
	Alzheimers Disease
	Integrin-mediated Cell Adhesion
References
Ref 543197	(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 8570).
Ref 543595	(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 2336).

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Drug Information