Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0SB6K
|
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| Former ID |
DIB008992
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| Drug Name |
DAT-582
|
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| Synonyms |
AS-5820
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| Drug Type |
Small molecular drug
|
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| Indication | Nausea [ICD10:R11] | Discontinued in Phase 2 | [1] | ||
| Company |
Dainippon Pharmaceutical Co Ltd
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| Structure |
|
Download2D MOL |
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| Formula |
C22H29Cl2N5O
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| Canonical SMILES |
c1(n[nH]c2c1cccc2)C(=O)N[C@H]1CN(Cc2cc(ccc2)C)CCN(C1)C.<br />Cl.Cl
|
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| CAS Number |
CAS 141034-42-6
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| PubChem Compound ID | |||||
| Target and Pathway | |||||
| Target(s) | 5-Hydroxytryptamine 3 receptor | Target Info | Antagonist | [2] | |
| References | |||||
| REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800001226) | ||||
| REF 2 | 5-HT3 receptor antagonist effects of DAT-582, (R) enantiomer of AS-5370. Eur J Pharmacol. 1992 Jun 17;216(3):435-40. | ||||
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