Drug General Information
Drug ID	D0T3UP
Former ID	DNC004184
Drug Name	1,3-Dihydro-naphtho[2,3-d]imidazol-2-one
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[528087]
Structure		Download 2D MOL 3D MOL
Formula	C11H8N2O
Canonical SMILES	C1=CC=C2C=C3C(=CC2=C1)NC(=O)N3
InChI	1S/C11H8N2O/c14-11-12-9-5-7-3-1-2-4-8(7)6-10(9)13-11/h1-6H,(H2,12,13,14)
InChIKey	HUOPXZLFTBYAML-UHFFFAOYSA-N
PubChem Compound ID	13724742
Target and Pathway
Target(s)	CGMP-inhibited 3',5'-cyclic phosphodiesterase A	Target Info	Inhibitor	[528087]
KEGG Pathway	Purine metabolism
	cGMP-PKG signaling pathway
	cAMP signaling pathway
	Morphine addiction
Reactome	cGMP effects
	G alpha (s) signalling events
WikiPathways	miR-targeted genes in muscle cell - TarBase
	miR-targeted genes in lymphocytes - TarBase
References
Ref 528087	J Med Chem. 1991 Sep;34(9):2906-16.1,3-Dihydro-2H-imidazo[4,5-b]quinolin-2-ones--inhibitors of blood platelet cAMP phosphodiesterase and induced aggregation.
Ref 528087	J Med Chem. 1991 Sep;34(9):2906-16.1,3-Dihydro-2H-imidazo[4,5-b]quinolin-2-ones--inhibitors of blood platelet cAMP phosphodiesterase and induced aggregation.

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