TTD | Drug: D0T5FY

Drug General Information
Drug ID	D0T5FY
Former ID	DNC012411
Drug Name	2,4-Dichloro-N-(4-phenyl-thiazol-2-yl)-benzamide
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[526099]
Structure		Download 2D MOL 3D MOL
Formula	C16H10Cl2N2OS
Canonical SMILES	C1=CC=C(C=C1)C2=CSC(=N2)NC(=O)C3=C(C=C(C=C3)Cl)Cl
InChI	1S/C16H10Cl2N2OS/c17-11-6-7-12(13(18)8-11)15(21)20-16-19-14(9-22-16)10-4-2-1-3-5-10/h1-9H,(H,19,20,21)
InChIKey	MWSDOEQEOIKHRL-UHFFFAOYSA-N
PubChem Compound ID	599553
Target and Pathway
Target(s)	Adenosine A1 receptor	Target Info	Inhibitor	[526099]
KEGG Pathway	cGMP-PKG signaling pathway
	cAMP signaling pathway
	Sphingolipid signaling pathway
	Neuroactive ligand-receptor interaction
	Morphine addiction
NetPath Pathway	TCR Signaling Pathway
NetPath Pathway	RANKL Signaling Pathway
PANTHER Pathway	Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
PANTHER Pathway	Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway
Reactome	Adenosine P1 receptors
Reactome	G alpha (i) signalling events
WikiPathways	Nucleotide GPCRs
	GPCRs, Class A Rhodopsin-like
	GPCR ligand binding
	GPCR downstream signaling
References
Ref 526099	Bioorg Med Chem Lett. 2001 Aug 6;11(15):2017-9.Substituted 4-phenyl-2-(phenylcarboxamido)-1,3-thiazole derivatives as antagonists for the adenosine A(1) receptor.
Ref 526099	Bioorg Med Chem Lett. 2001 Aug 6;11(15):2017-9.Substituted 4-phenyl-2-(phenylcarboxamido)-1,3-thiazole derivatives as antagonists for the adenosine A(1) receptor.

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Drug Information