Drug Information

Drug General Information
Drug ID
D0U2CV
Former ID
DNC001459
Drug Name
Trapidil
Drug Type
Small molecular drug
Indication Discovery agent Phase 4 [522688]
Structure
Download
2D MOL

3D MOL
Formula
C10H15N5
Canonical SMILES
CCN(CC)C1=CC(=NC2=NC=NN12)C
InChI
1S/C10H15N5/c1-4-14(5-2)9-6-8(3)13-10-11-7-12-15(9)10/h6-7H,4-5H2,1-3H3
InChIKey
GSNOZLZNQMLSKJ-UHFFFAOYSA-N
CAS Number
CAS 15421-84-8
PubChem Compound ID
5531
PubChem Substance ID
866458, 5659229, 7848283, 8153404, 11112623, 11467040, 11468160, 11486770, 14745540, 14748788, 29224573, 47810921, 47959939, 48110614, 48259417, 49699027, 50057667, 50086436, 50100500, 56365869, 57322829, 74813390, 85787550, 88858725, 92126029, 92133451, 93815048, 103371622, 103914683, 104309497, 105640614, 117431105, 121363700, 124799773, 125432948, 126922620, 127999928, 134340574, 134340639, 134991679, 137248780, 144204129, 162249201, 162796478, 169428974, 170465770, 175612102, 178126772, 179149421, 184547380
SuperDrug ATC ID
C01DX11
SuperDrug CAS ID
cas=015421848
Target and Pathway
Target(s) Platelet-derived growth factor receptor Target Info Inhibitor [536783]
References
Ref 522688ClinicalTrials.gov (NCT00914420) Optical Coherence Tomography (OCT) Evaluation of Re-endothelization: A Comparison of the Intrepide Stent Versus Taxus . U.S. National Institutes of Health.
Ref 536783Osteitis fibrosa is mediated by Platelet-Derived Growth Factor-A via a phosphoinositide 3-kinase-dependent signaling pathway in a rat model for chronic hyperparathyroidism. Endocrinology. 2008 Nov;149(11):5735-46. Epub 2008 Jul 17.

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