Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0U5LL
|
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| Former ID |
DIB019060
|
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| Drug Name |
cannabinol
|
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| Drug Type |
Small molecular drug
|
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| Indication | Discovery agent | Investigative | [1] | ||
| Structure |
|
Download2D MOL |
|||
| Formula |
C21H26O2
|
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| InChI |
InChI=1S/C21H26O2/c1-5-6-7-8-15-12-18(22)20-16-11-14(2)9-10-17(16)21(3,4)23-19(20)13-15/h9-13,22H,5-8H2,1-4H3
|
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| InChIKey |
VBGLYOIFKLUMQG-UHFFFAOYSA-N
|
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| PubChem Compound ID | |||||
| PubChem Substance ID |
9782, 423125, 841254, 4688526, 8150127, 8151685, 10525129, 11336147, 11361386, 11462358, 14752180, 24892874, 24892909, 29221705, 47810837, 49962236, 50113074, 50561854, 57309734, 57321366, 57654033, 57654037, 74382082, 85208997, 99302060, 103274782, 103856333, 103956704, 104300896, 129450190, 134977205, 135650052, 137003699, 142472555, 144207035, 162220714, 164837692, 176262245, 179148437, 198959880, 223439214, 224904146, 226492602, 241090056, 241376281, 250114444, 252157042
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| Target and Pathway | |||||
| Target(s) | TRPV2 | Target Info | Activator | [2] | |
| Cannabinoid receptor 1 | Target Info | Agonist | [3] | ||
| KEGG Pathway | Rap1 signaling pathway | ||||
| Neuroactive ligand-receptor interaction | |||||
| Retrograde endocannabinoid signaling | |||||
| PANTHER Pathway | Endogenous cannabinoid signaling | ||||
| Pathway Interaction Database | N-cadherin signaling events | ||||
| Reactome | Class A/1 (Rhodopsin-like receptors) | ||||
| G alpha (i) signalling events | |||||
| WikiPathways | GPCRs, Class A Rhodopsin-like | ||||
| Small Ligand GPCRs | |||||
| BDNF signaling pathway | |||||
| GPCR ligand binding | |||||
| GPCR downstream signaling | |||||
| GPCRs, Other | |||||
| References | |||||
| REF 1 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 740). | ||||
| REF 2 | TRPV2 is activated by cannabidiol and mediates CGRP release in cultured rat dorsal root ganglion neurons. J Neurosci. 2008 Jun 11;28(24):6231-8. | ||||
| REF 3 | Evaluation of binding in a transfected cell line expressing a peripheral cannabinoid receptor (CB2): identification of cannabinoid receptor subtype selective ligands. J Pharmacol Exp Ther. 1996 Sep;278(3):989-99. | ||||
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