Drug Information

Drug General Information
Drug ID
D0U7EQ
Former ID
DIB018218
Drug Name
[3H]2MeSADP
Synonyms
[3H]2-methylthio-ADP
Drug Type
Small molecular drug
Indication Discovery agent Investigative [539113]
Formula
C11H17N5O10P2S
InChI
InChI=1S/C11H17N5O10P2S/c1-29-11-14-8(12)5-9(15-11)16(3-13-5)10-7(18)6(17)4(25-10)2-24-28(22,23)26-27(19,20)21/h3-4,6-7,10,17-18H,2H2,1H3,(H,22,23)(H2,12,14,15)(H2,19,20,21)/t4-,6-,7-,10-/m1/s1
InChIKey
WLMZTKAZJUWXCB-KQYNXXCUSA-N
PubChem Compound ID
121990
Target and Pathway
Target(s) P2Y purinoceptor 1 Target Info Agonist [526120]
P2Y purinoceptor 12 Target Info Agonist [526120]
KEGG Pathway Rap1 signaling pathway
Neuroactive ligand-receptor interaction
Platelet activationhsa04611:Platelet activation
Reactome G alpha (q) signalling events
P2Y receptors
ADP signalling through P2Y purinoceptor 1R-HSA-417957:P2Y receptors
G alpha (i) signalling events
WikiPathways Nucleotide GPCRs
GPCRs, Class A Rhodopsin-like
Gastrin-CREB signalling pathway via PKC and MAPK
Signal amplification
GPCR ligand binding
GPCR downstream signalingWP455:GPCRs, Class A Rhodopsin-like
GPCR downstream signaling
References
Ref 539113(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 1763).
Ref 526120Molecular cloning of the platelet P2T(AC) ADP receptor: pharmacological comparison with another ADP receptor, the P2Y(1) receptor. Mol Pharmacol. 2001 Sep;60(3):432-9.

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