Drug Information
Drug General Information | |||||
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Drug ID |
D0U7PS
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Former ID |
DCL000375
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Drug Name |
GSK256066
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Synonyms |
GSK-256066
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Drug Type |
Small molecular drug
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Indication | Chronic obstructive pulmonary disease; Asthma [ICD9: 490-492, 493, 494-496; ICD10:J40-J44, J47, J45] | Discontinued in Phase 2 | [548294] | ||
Company |
GSK
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Structure |
Download2D MOL |
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Formula |
C27H26N4O5S
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Canonical SMILES |
CC1=C2C(=CC(=C1)S(=O)(=O)C3=CC=CC(=C3)C(=O)N(C)C)C(=C(C<br />=N2)C(=O)N)NC4=CC(=CC=C4)OC
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InChI |
1S/C27H26N4O5S/c1-16-11-21(37(34,35)20-10-5-7-17(12-20)27(33)31(2)3)14-22-24(16)29-15-23(26(28)32)25(22)30-18-8-6-9-19(13-18)36-4/h5-15H,1-4H3,(H2,28,32)(H,29,30)
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InChIKey |
JFHROPTYMMSOLG-UHFFFAOYSA-N
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PubChem Compound ID | |||||
PubChem Substance ID |
14787174, 24129924, 44926098, 75157187, 103704123, 124360777, 125164690, 125653374, 131326858, 134339024, 136340322, 136349521, 136367652, 136920333, 137685009, 144116030, 152258227, 160647063, 162011384, 162038031, 162202759, 163364025, 163642651, 163913562, 164194085, 170482606, 174006286, 174530826, 180191800, 185998827, 198983498, 223682017, 223705159, 227387094, 242059766, 242591500, 247189701, 251963086, 251971295, 252110118, 252215508, 252449266, 252451559
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Target and Pathway | |||||
Target(s) | CAMP-specific 3',5'-cyclic phosphodiesterase 4A | Target Info | Inhibitor | [550963] | |
WikiPathways | G Protein Signaling Pathways | ||||
References |
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