Drug General Information
Drug ID	D0U8RZ
Former ID	DNC004866
Drug Name	2-[1-(2-Chloro-phenyl)-1H-pyrrol-2-yl]-ethylamine
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[527627]
Structure		Download 2D MOL 3D MOL
Formula	C12H13ClN2
Canonical SMILES	C1=CC=C(C(=C1)N2C=CC=C2CCN)Cl
InChI	1S/C12H13ClN2/c13-11-5-1-2-6-12(11)15-9-3-4-10(15)7-8-14/h1-6,9H,7-8,14H2
InChIKey	QDZRUXBRYDSOHU-UHFFFAOYSA-N
PubChem Compound ID	44388886
Target and Pathway
Target(s)	5-hydroxytryptamine 7 receptor	Target Info	Inhibitor	[527627]
KEGG Pathway	Ras signaling pathway
	Calcium signaling pathway
	Neuroactive ligand-receptor interaction
	Serotonergic synapse
PANTHER Pathway	Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
PathWhiz Pathway	Excitatory Neural Signalling Through 5-HTR 7 and Serotonin
Reactome	Serotonin receptors
	G alpha (s) signalling events
WikiPathways	Serotonin Receptor 4/6/7 and NR3C Signaling
	Monoamine GPCRs
	GPCRs, Class A Rhodopsin-like
	GPCR ligand binding
	GPCR downstream signaling
	GPCRs, Other
References
Ref 527627	Bioorg Med Chem Lett. 2005 Aug 15;15(16):3753-7.Phenylpyrroles, a new chemolibrary virtual screening class of 5-HT7 receptor ligands.
Ref 527627	Bioorg Med Chem Lett. 2005 Aug 15;15(16):3753-7.Phenylpyrroles, a new chemolibrary virtual screening class of 5-HT7 receptor ligands.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.