Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0V1PD
|
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| Former ID |
DIB019638
|
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| Drug Name |
cooling agent 10
|
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| Synonyms |
(-)-menthoxypropane-1,2-diol
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| Drug Type |
Small molecular drug
|
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| Indication | Discovery agent | Investigative | [1] | ||
| Structure |
|
Download2D MOL |
|||
| Formula |
C13H26O3
|
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| InChI |
InChI=1S/C13H26O3/c1-9(2)12-5-4-10(3)6-13(12)16-8-11(15)7-14/h9-15H,4-8H2,1-3H3
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| InChIKey |
MDVYIGJINBYKOM-UHFFFAOYSA-N
|
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| PubChem Compound ID | |||||
| PubChem Substance ID |
11528546, 11654116, 14892476, 39384567, 53801004, 57362115, 76972069, 114150221, 125349471, 125569066, 126683762, 128581553, 135569459, 137122284, 142012475, 151982075, 162222565, 162766585, 163812828, 172833562, 172835769, 176312015, 184534521, 184603009, 204403238, 223683728, 226483679, 241151518, 249583751, 251880699
|
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| Target and Pathway | |||||
| Target(s) | TRPM8 protein | Target Info | Activator | [2] | |
| KEGG Pathway | Inflammatory mediator regulation of TRP channels | ||||
| Reactome | TRP channels | ||||
| References | |||||
| REF 1 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 2463). | ||||
| REF 2 | Characterization of the mouse cold-menthol receptor TRPM8 and vanilloid receptor type-1 VR1 using a fluorometric imaging plate reader (FLIPR) assay. Br J Pharmacol. 2004 Feb;141(4):737-45. Epub 2004Feb 2. | ||||
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