Drug General Information
Drug ID
D0V9MI
Former ID
DNC005487
Drug Name
BAY-60-7550
Drug Type
Small molecular drug
Indication Discovery agent Investigative [468210]
Structure
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2D MOL

3D MOL

Formula
C27H32N4O4
InChI
InChI=1S/C27H32N4O4/c1-17-25-27(33)29-24(16-20-13-14-22(34-3)23(15-20)35-4)30-31(25)26(28-17)21(18(2)32)12-8-11-19-9-6-5-7-10-19/h5-7,9-10,13-15,18,21,32H,8,11-12,16H2,1-4H3,(H,29,30,33)/t18-,21+/m1/s1
InChIKey
MYTWFJKBZGMYCS-NQIIRXRSSA-N
PubChem Compound ID
PubChem Substance ID
Target and Pathway
Target(s) CGMP-dependent3',5'-cyclic phosphodiesterase Target Info Inhibitor [527549]
KEGG Pathway Purine metabolism
cGMP-PKG signaling pathway
Morphine addiction
NetPath Pathway TSH Signaling Pathway
Reactome cGMP effects
G alpha (s) signalling events
References
Ref 468210(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 5147).
Ref 527549J Med Chem. 2005 May 19;48(10):3449-62.The next generation of phosphodiesterase inhibitors: structural clues to ligand and substrate selectivity of phosphodiesterases.

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