Drug Information
Drug General Information | |||||
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Drug ID |
D0VJ5N
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Former ID |
DCL000223
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Drug Name |
SB-705498
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Drug Type |
Small molecular drug
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Company |
GlaxoSmithKline
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Structure |
Download2D MOL |
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Formula |
C17H16BrF3N4O
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InChI |
InChI=1S/C17H16BrF3N4O/c18-13-3-1-2-4-14(13)24-16(26)23-12-7-8-25(10-12)15-6-5-11(9-22-15)17(19,20)21/h1-6,9,12H,7-8,10H2,(H2,23,24,26)/t12-/m1/s1
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InChIKey |
JYILLRHXRVTRSH-GFCCVEGCSA-N
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PubChem Compound ID | |||||
PubChem Substance ID |
14880783, 15329850, 24191010, 24714966, 45982146, 49688578, 80688310, 103489680, 134338885, 135302994, 136340373, 137663487, 141108962, 152159579, 152258263, 160647099, 162011660, 162205200, 174007206, 174529520, 178101128, 186007046, 189024877, 198989585, 208265534, 223705156, 224286843, 227570003, 242588168, 246888321, 249735426, 251963246, 252151430, 252811273
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Target and Pathway | |||||
Target(s) | Vanilloid receptor 1 | Target Info | Blocker | [536410], [537396] | |
NetPath Pathway | IL2 Signaling Pathway | ||||
Pathway Interaction Database | Trk receptor signaling mediated by the MAPK pathway | ||||
Trk receptor signaling mediated by PI3K and PLC-gamma | |||||
Reactome | TRP channels | ||||
References | |||||
Ref 467650 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 4311). | ||||
Ref 548140 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800022354) |
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