Drug Information
Drug General Information | |||||
---|---|---|---|---|---|
Drug ID |
D0W3GL
|
||||
Former ID |
DNC005420
|
||||
Drug Name |
SR-147778
|
||||
Drug Type |
Small molecular drug
|
||||
Indication | Obesity [ICD9: 278; ICD10:E66] | Phase 2 | [1] | ||
Structure |
Download2D MOL |
||||
Formula |
C23H23BrCl2N4O
|
||||
Canonical SMILES |
CCC1=C(N(N=C1C(=O)NN2CCCCC2)C3=C(C=C(C=C3)Cl)Cl)C4=CC=C<br />(C=C4)Br
|
||||
InChI |
1S/C23H23BrCl2N4O/c1-2-18-21(23(31)28-29-12-4-3-5-13-29)27-30(20-11-10-17(25)14-19(20)26)22(18)15-6-8-16(24)9-7-15/h6-11,14H,2-5,12-13H2,1H3,(H,28,31)
|
||||
InChIKey |
HMXDWDSNPRNUKI-UHFFFAOYSA-N
|
||||
PubChem Compound ID | |||||
Target and Pathway | |||||
Target(s) | Cannabinoid receptor 1 | Target Info | Modulator | ||
KEGG Pathway | Rap1 signaling pathway | ||||
Neuroactive ligand-receptor interaction | |||||
Retrograde endocannabinoid signaling | |||||
PANTHER Pathway | Endogenous cannabinoid signaling | ||||
Pathway Interaction Database | N-cadherin signaling events | ||||
Reactome | Class A/1 (Rhodopsin-like receptors) | ||||
G alpha (i) signalling events | |||||
WikiPathways | GPCRs, Class A Rhodopsin-like | ||||
Small Ligand GPCRs | |||||
BDNF signaling pathway | |||||
GPCR ligand binding | |||||
GPCR downstream signaling | |||||
GPCRs, Other | |||||
References | |||||
REF 1 | ClinicalTrials.gov (NCT00239174) A Multicenter Study to Evaluate the Efficacy and Safety of of Four Doses of SR147778 in Obese Patients. U.S. National Institutes of Health. |
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.