Drug General Information
Drug ID	D0WP6A
Former ID	DNC006332
Drug Name	3-hydroxy-4-methyl-6H-benzo[c]chromen-6-one
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[527966]
Structure		Download 2D MOL 3D MOL
Formula	C14H10O3
Canonical SMILES	CC1=C(C=CC2=C1OC(=O)C3=CC=CC=C23)O
InChI	1S/C14H10O3/c1-8-12(15)7-6-10-9-4-2-3-5-11(9)14(16)17-13(8)10/h2-7,15H,1H3
InChIKey	LAVHXGNOROFSCU-UHFFFAOYSA-N
PubChem Compound ID	5348729
Target and Pathway
Target(s)	Estrogen receptor beta	Target Info	Inhibitor	[527966]
KEGG Pathway	Estrogen signaling pathway
	Prolactin signaling pathway
Pathway Interaction Database	Plasma membrane estrogen receptor signaling
	Validated nuclear estrogen receptor beta network
	Validated nuclear estrogen receptor alpha network
Reactome	Nuclear Receptor transcription pathway
WikiPathways	SIDS Susceptibility Pathways
	Ovarian Infertility Genes
	Integrated Pancreatic Cancer Pathway
	Nuclear Receptors
References
Ref 527966	Bioorg Med Chem Lett. 2006 Mar 15;16(6):1468-72. Epub 2006 Jan 18.6H-Benzo[c]chromen-6-one derivatives as selective ERbeta agonists.
Ref 527966	Bioorg Med Chem Lett. 2006 Mar 15;16(6):1468-72. Epub 2006 Jan 18.6H-Benzo[c]chromen-6-one derivatives as selective ERbeta agonists.

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