Drug Information

Drug General Information
Drug ID
D0X7JK
Former ID
DIB019858
Drug Name
TCS-359
Synonyms
TCS 359; TCS-359
Drug Type
Small molecular drug
Indication Discovery agent Investigative [528114]
Structure
Download
2D MOL
Formula
C18H20N2O4S
InChI
InChI=1S/C18H20N2O4S/c1-23-12-8-7-10(9-13(12)24-2)17(22)20-18-15(16(19)21)11-5-3-4-6-14(11)25-18/h7-9H,3-6H2,1-2H3,(H2,19,21)(H,20,22)
InChIKey
FSPQCTGGIANIJZ-UHFFFAOYSA-N
PubChem Compound ID
1048845
PubChem Substance ID
1321210, 3230603, 3354452, 4079009, 4906390, 8751927, 17000751, 24332340, 24724465, 25749477, 26758701, 40810380, 47321816, 47767674, 50112926, 51240179, 53800921, 57899417, 85787670, 87717363, 99302675, 103490072, 104069325, 104840163, 110180211, 124579771, 124659182, 134964526, 135698114, 142683481, 162023432, 162247974, 162312753, 163123665, 163688142, 164041757, 164862696, 169389923, 172820848, 178102593, 179050822, 185998766, 204372562, 208265128, 208265462, 210275001, 210280639, 223379700, 223489746, 233817153
Target and Pathway
Target(s) FL cytokine receptor Target Info Inhibitor [528114]
KEGG Pathway Cytokine-cytokine receptor interaction
Hematopoietic cell lineage
Pathways in cancer
Transcriptional misregulation in cancer
Acute myeloid leukemia
Central carbon metabolism in cancer
References
Ref 528114Bioorg Med Chem Lett. 2006 Jun 15;16(12):3282-6. Epub 2006 Mar 31.Identification of 2-acylaminothiophene-3-carboxamides as potent inhibitors of FLT3.
Ref 528114Bioorg Med Chem Lett. 2006 Jun 15;16(12):3282-6. Epub 2006 Mar 31.Identification of 2-acylaminothiophene-3-carboxamides as potent inhibitors of FLT3.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.