Drug General Information
Drug ID	D0X7SD
Former ID	DNC010462
Drug Name	2-(Biphenyl-2-yloxy)-N,N-dimethylethanamine
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[530699]
Structure		Download 2D MOL 3D MOL
Formula	C16H19NO
Canonical SMILES	CN(C)CCOC1=CC=CC=C1C2=CC=CC=C2
InChI	1S/C16H19NO/c1-17(2)12-13-18-16-11-7-6-10-15(16)14-8-4-3-5-9-14/h3-11H,12-13H2,1-2H3
InChIKey	HEGXUUYKFGNKJB-UHFFFAOYSA-N
PubChem Compound ID	888197
Target and Pathway
Target(s)	5-hydroxytryptamine 7 receptor	Target Info	Inhibitor	[530699]
KEGG Pathway	Ras signaling pathway
	Calcium signaling pathway
	Neuroactive ligand-receptor interaction
	Serotonergic synapse
PANTHER Pathway	Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
PathWhiz Pathway	Excitatory Neural Signalling Through 5-HTR 7 and Serotonin
Reactome	Serotonin receptors
	G alpha (s) signalling events
WikiPathways	Serotonin Receptor 4/6/7 and NR3C Signaling
	Monoamine GPCRs
	GPCRs, Class A Rhodopsin-like
	GPCR ligand binding
	GPCR downstream signaling
	GPCRs, Other
References
Ref 530699	Bioorg Med Chem. 2010 Mar 1;18(5):1958-67. Epub 2010 Jan 18.SAR studies on new bis-aryls 5-HT7 ligands: Synthesis and molecular modeling.
Ref 530699	Bioorg Med Chem. 2010 Mar 1;18(5):1958-67. Epub 2010 Jan 18.SAR studies on new bis-aryls 5-HT7 ligands: Synthesis and molecular modeling.

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