TTD | Drug: D0XD4N

Drug General Information
Drug ID	D0XD4N
Former ID	DIB008256
Drug Name	ERB-002
Synonyms	ERB-002; ERB-131; ERb agonists, ACADIA; Estrogen receptor beta agonists, ACADIA
Indication	Inflammatory disease [ICD9: 140-229, 147, 173, 573.3, 710-719; ICD10:C11, C44, K75.9, M00-M25]		Investigative	[543899]
Company	ACADIA Pharmaceuticals Inc
Structure		Download 2D MOL 3D MOL
Canonical SMILES	C1CC(CCC1)(c1ccc(cc1)O)c1ccccc1
Target and Pathway
Target(s)	Estrogen receptor beta	Target Info	Agonist	[543899]
KEGG Pathway	Estrogen signaling pathway
KEGG Pathway	Prolactin signaling pathway
Pathway Interaction Database	Plasma membrane estrogen receptor signaling
	Validated nuclear estrogen receptor beta network
	Validated nuclear estrogen receptor alpha network
Reactome	Nuclear Receptor transcription pathway
WikiPathways	SIDS Susceptibility Pathways
	Ovarian Infertility Genes
	Integrated Pancreatic Cancer Pathway
	Nuclear Receptors
References
Ref 543899	(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 621).
Ref 543899	(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 621).

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Drug Information