Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0XS4H
|
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| Former ID |
DNC002427
|
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| Drug Name |
7,8-Dihydro-L-Biopterin
|
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| Drug Type |
Small molecular drug
|
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| Indication | Discovery agent | Investigative | [1] | ||
| Structure |
|
Download2D MOL |
|||
| Formula |
C9H13N5O3
|
||||
| Canonical SMILES |
CC(C(C1=NC2=C(NC1)NC(=NC2=O)N)O)O
|
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| InChI |
1S/C9H13N5O3/c1-3(15)6(16)4-2-11-7-5(12-4)8(17)14-9(10)13-7/h3,6,15-16H,2H2,1H3,(H4,10,11,13,14,17)
|
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| InChIKey |
FEMXZDUTFRTWPE-UHFFFAOYSA-N
|
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| CAS Number |
CAS 6779-87-9
|
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| PubChem Compound ID | |||||
| PubChem Substance ID | |||||
| Target and Pathway | |||||
| Target(s) | Nitric oxide synthase, inducible | Target Info | Inhibitor | [1] | |
| BioCyc Pathway | Citrulline-nitric oxide cycle | ||||
| KEGG Pathway | Arginine biosynthesis | ||||
| Arginine and proline metabolism | |||||
| Metabolic pathways | |||||
| Calcium signaling pathway | |||||
| HIF-1 signaling pathway | |||||
| Peroxisome | |||||
| Salmonella infection | |||||
| Pertussis | |||||
| Leishmaniasis | |||||
| Chagas disease (American trypanosomiasis) | |||||
| Toxoplasmosis | |||||
| Amoebiasis | |||||
| Tuberculosis | |||||
| Pathways in cancer | |||||
| Small cell lung cancer | |||||
| NetPath Pathway | IL1 Signaling Pathway | ||||
| IL2 Signaling Pathway | |||||
| Pathway Interaction Database | IL12-mediated signaling events | ||||
| Alpha9 beta1 integrin signaling events | |||||
| ATF-2 transcription factor network | |||||
| IL23-mediated signaling events | |||||
| Signaling mediated by p38-alpha and p38-beta | |||||
| HIF-1-alpha transcription factor network | |||||
| Reactome | ROS production in response to bacteria | ||||
| Nitric oxide stimulates guanylate cyclase | |||||
| WikiPathways | Type II interferon signaling (IFNG) | ||||
| Spinal Cord Injury | |||||
| AGE/RAGE pathway | |||||
| Effects of Nitric Oxide | |||||
| References | |||||
| REF 1 | DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Nucleic Acids Res. 2011 Jan;39(Database issue):D1035-4. Nucleic Acids Res. 2011 January | ||||
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