Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0XW6Y
|
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| Former ID |
DIB004474
|
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| Drug Name |
S-38093
|
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| Synonyms |
S-41150; S-38471-1; S-750-1; Histamine H3 antagonists (sleep/cognitive disorders), Servier
|
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| Indication | Alzheimer disease [ICD9: 331; ICD10:G30] | Phase 2 | [1] | ||
| Company |
Servier
|
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| Structure |
|
Download2D MOL |
|||
| Canonical SMILES |
C1CCN2C(C1)CN(CC2)CCCCOc1ccc(cc1)C(=O)c1ccc(cc1)/C(=N/O<br />)/C
|
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| Target and Pathway | |||||
| Target(s) | Histamine H3 receptor | Target Info | Antagonist | [2] | |
| KEGG Pathway | Neuroactive ligand-receptor interaction | ||||
| Reactome | Histamine receptors | ||||
| G alpha (i) signalling events | |||||
| WikiPathways | Monoamine Transport | ||||
| GPCRs, Class A Rhodopsin-like | |||||
| GPCR ligand binding | |||||
| GPCR downstream signaling | |||||
| References | |||||
| REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800032202) | ||||
| REF 2 | Histamine H3 Receptors and Sleep-Wake Regulation. JPET January 2011 vol. 336 no. 1 17-23. | ||||
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