Drug Information
Drug General Information | |||||
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Drug ID |
D0Y0RW
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Former ID |
DIB010664
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Drug Name |
Alniditan
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Synonyms |
Pasmigren; R-091274
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Drug Type |
Small molecular drug
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Company |
Janssen-Cilag Ltd
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Structure |
Download2D MOL |
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Formula |
C17H26N4O
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InChI |
InChI=1S/C17H26N4O/c1-2-6-16-14(5-1)7-8-15(22-16)13-18-9-3-10-19-17-20-11-4-12-21-17/h1-2,5-6,15,18H,3-4,7-13H2,(H2,19,20,21)/t15-/m1/s1
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InChIKey |
QVSXOXCYXPQXMF-OAHLLOKOSA-N
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CAS Number |
CAS 152317-89-0
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PubChem Compound ID | |||||
PubChem Substance ID | |||||
Target and Pathway | |||||
Target(s) | 5-hydroxytryptamine 1D receptor | Target Info | Agonist | [534635], [551730] | |
References | |||||
Ref 538712 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 120). | ||||
Ref 546088 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800006286) | ||||
Ref 534635 | Br J Pharmacol. 1998 Apr;123(8):1655-65.Agonistic properties of alniditan, sumatriptan and dihydroergotamine on human 5-HT1B and 5-HT1D receptors expressed in various mammalian cell lines. | ||||
Ref 551730 | Sustained pain relief with dihydroergotamine in migraine is potentially due to persistent binding to 5-HT1B and 5-HT1D receptors. . The Journal of Headache and Pain 201314(Suppl 1):P75. |
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