Drug Information
Drug General Information | |||||
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Drug ID |
D0Y3RY
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Former ID |
DIB005376
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Drug Name |
R-1578
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Synonyms |
RG-1578; RG-1578); MGluR2 antagonist (depression), Roche; MGluR2 antagonist (Alzheimer's disease/depression), Roche
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Indication | Mood disorder [ICD10:F30-F39] | Discontinued in Phase 2 | [549263] | ||
Company |
Abiocode; Hoffmann-La Roche AG
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Target and Pathway | |||||
Target(s) | Metabotropic glutamate receptor3 | Target Info | Antagonist | [551608] | |
Metabotropic glutamate receptor 2 | Target Info | Antagonist | [551608] | ||
PANTHER Pathway | Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway | ||||
Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway | |||||
Ionotropic glutamate receptor pathway | |||||
Metabotropic glutamate receptor group II pathwayP00026:Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway | |||||
Metabotropic glutamate receptor group II pathway | |||||
References |
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