Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0Y5QO
|
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| Former ID |
DIB012490
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| Drug Name |
GK-128
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| Indication | Emesis [ICD9: 787; ICD10:R11] | Terminated | [1] | ||
| Company |
Taisho Pharmaceutical Co Ltd
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| Structure |
|
Download2D MOL |
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| Canonical SMILES |
c1(c(=O)c2c3c(ccc2sc1)cccc3)Cn1c(ncc1)C.Cl
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| CAS Number |
CAS 139958-03-5
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| Target and Pathway | |||||
| Target(s) | 5-Hydroxytryptamine 3 receptor | Target Info | Modulator | [2] | |
| References | |||||
| REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800002051) | ||||
| REF 2 | Effect of a novel 5-hydroxytryptamine3 (5-HT3) receptor antagonist, GK-128, on 5-HT3 receptors mediating contractions and relaxations in guinea-pig distal colon. Gen Pharmacol. 1997 Sep;29(3):353-9. | ||||
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