Drug Information
Drug General Information | |||||
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Drug ID |
D0Y5ZT
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Former ID |
DIB013290
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Drug Name |
KRP-203
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Synonyms |
KNF-299; KRP-203-P prodrug, Kyorin
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Drug Type |
Small molecular drug
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Indication | Cutaneous lupus erythematosus [ICD9: 710; ICD10:M32] | Phase 2 | [523356] | ||
Company |
Kyorin Pharmaceutical Co Ltd
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Structure |
Download2D MOL |
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Formula |
C24H26ClNO3S
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Canonical SMILES |
NC(CO)(CCc1ccc(Sc2cccc(OCc3ccccc3)c2)cc1Cl)CO.Cl
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CAS Number |
CAS 509088-69-1
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PubChem Compound ID | |||||
Target and Pathway | |||||
Target(s) | Sphingosine 1-phosphate receptor 1 | Target Info | Agonist | [532341], [532456] | |
References | |||||
Ref 532341 | KRP-203, sphingosine 1-phosphate receptor type 1 agonist, ameliorates atherosclerosis in LDL-R-/- mice. Arterioscler Thromb Vasc Biol. 2013 Jul;33(7):1505-12. | ||||
Ref 532456 | Targeting the sphingosine-1-phosphate axis in cancer, inflammation and beyond. Nat Rev Drug Discov. 2013 Sep;12(9):688-702. |
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