Drug Information

Drug General Information
Drug ID
D0Y6IJ
Former ID
DIB004516
Drug Name
Ro-48-5545
Synonyms
Bridged beta lactamase inhibitors, Roche; Ro-47-5325; Ro-48-1256; Ro-48-5545; Ro-48-7953
Indication Bacterial infections [ICD9: 001-009, 010-018, 020-027, 030-041, 080-088, 090-099, 100-104; ICD10:A00-B99] Terminated [546440]
Company
F Hoffmann-La Roche Ltd
Structure
Download
2D MOL

3D MOL
Canonical SMILES
N1(C(=O)[C@@H]2[C@H]1CCN2C(=O)NC1CCNCC1)S(=O)(=O)O
Target and Pathway
Target(s) Beta-lactamase Target Info Inhibitor [534491]
References
Ref 546440Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800008139)
Ref 534491Potentiation of beta-lactams against Pseudomonas aeruginosa strains by Ro 48-1256, a bridged monobactam inhibitor of AmpC beta-lactamases. J Antimicrob Chemother. 1997 Sep;40(3):335-43.

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