Drug Information

Drug General Information
Drug ID
D0YE5K
Former ID
DNC011504
Drug Name
N-(3-Phenyl-[1,2,4]thiadiazol-5-yl)-benzamide
Drug Type
Small molecular drug
Indication Discovery agent Investigative [526011]
Structure
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2D MOL

3D MOL
Formula
C15H11N3OS
Canonical SMILES
C1=CC=C(C=C1)C2=NSC(=N2)NC(=O)C3=CC=CC=C3
InChI
1S/C15H11N3OS/c19-14(12-9-5-2-6-10-12)17-15-16-13(18-20-15)11-7-3-1-4-8-11/h1-10H,(H,16,17,18,19)
InChIKey
AYSLYXJUYHXKHV-UHFFFAOYSA-N
PubChem Compound ID
2241548
Target and Pathway
Target(s) Adenosine A2a receptor Target Info Inhibitor [526011]
KEGG Pathway Rap1 signaling pathway
Calcium signaling pathway
cAMP signaling pathway
Neuroactive ligand-receptor interaction
Vascular smooth muscle contraction
Parkinson's disease
Alcoholism
Pathway Interaction Database HIF-2-alpha transcription factor network
PathWhiz Pathway Intracellular Signalling Through Adenosine Receptor A2a and Adenosine
Reactome NGF-independant TRKA activation
Adenosine P1 receptors
G alpha (s) signalling events
Surfactant metabolism
WikiPathways Nucleotide GPCRs
Monoamine Transport
GPCRs, Class A Rhodopsin-like
NGF signalling via TRKA from the plasma membrane
GPCR ligand binding
GPCR downstream signaling
GPCRs, Other
References
Ref 526011J Med Chem. 2001 Mar 1;44(5):749-62.Thiazole and thiadiazole analogues as a novel class of adenosine receptor antagonists.
Ref 526011J Med Chem. 2001 Mar 1;44(5):749-62.Thiazole and thiadiazole analogues as a novel class of adenosine receptor antagonists.

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