Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0YF6L
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| Former ID |
DIB001259
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| Drug Name |
KST-5468
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| Synonyms |
KST-5468; T-type calcium channel antagonist (pain); T-type calcium channel antagonist (pain), SNU/KIST
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| Indication | Pain [ICD9: 338, 356.0, 356.8,780; ICD10:G64, G90.0, R52, G89] | Investigative | [1] | ||
| Company |
Seoul National University
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| Structure |
|
Download2D MOL |
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| Canonical SMILES |
n1(nc(cc1CC(C)C)CNC(=O)CN1CCN(CC1)c1ccccc1)c1ccccc1
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| Target and Pathway | |||||
| Target(s) | Voltage-dependent T-type calcium channel subunit alpha-1H | Target Info | Antagonist | [1] | |
| KEGG Pathway | MAPK signaling pathway | ||||
| Calcium signaling pathway | |||||
| Circadian entrainment | |||||
| PathWhiz Pathway | Muscle/Heart Contraction | ||||
| Reactome | NCAM1 interactions | ||||
| WikiPathways | Corticotropin-releasing hormone | ||||
| NCAM signaling for neurite out-growth | |||||
| References | |||||
| REF 1 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 536). | ||||
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