Drug Information
Drug General Information | |||||
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Drug ID |
D0YH0N
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Former ID |
DIB005117
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Drug Name |
Metadoxine
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Synonyms |
MG01CI; Metadoxine (oral sustained release, ADHD); Metadoxine (oral extended release, ADHD), Alcobra; Metadoxine (oral sustained release, ADHD), Alcobra
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Drug Type |
Small molecular drug
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Company |
Alcobra
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Structure |
Download2D MOL |
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Formula |
C13H18N2O6
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Canonical SMILES |
c1(c(cnc(c1O)C)CO)CO.[C@H]1(CCC(=O)N1)C(=O)O
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CAS Number |
CAS 74536-44-0
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PubChem Compound ID | |||||
Target and Pathway | |||||
Target(s) | Sodium- and chloride-dependent GABA transporter 1 | Target Info | Modulator | ||
KEGG Pathway | GABAergic synapse | ||||
WikiPathways | Monoamine Transport | ||||
NRF2 pathway | |||||
References | |||||
Ref 524626 | ClinicalTrials.gov (NCT02051842) Effect of Metadoxine on Oxidative Stress in Non-alcoholic Hepatic Steatosis. U.S. National Institutes of Health. | ||||
Ref 531706 | Preliminary findings on the use of metadoxine for the treatment of alcohol dependence and alcoholic liver disease. Hum Psychopharmacol. 2011 Dec;26(8):554-9. |
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