Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0Z1TF
|
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| Former ID |
DIB005785
|
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| Drug Name |
Ro-25-4094
|
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| Drug Type |
Small molecular drug
|
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| Indication | Inflammatory disease [ICD9: 140-229, 147, 173, 573.3, 710-719; ICD10:C11, C44, K75.9, M00-M25] | Terminated | [1] | ||
| Company |
Roche Holding AG
|
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| Structure |
|
Download2D MOL |
|||
| Formula |
C33H44O8
|
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| Canonical SMILES |
c12c(C(=O)CCO2)ccc(c1CCC)OCCCCCCc1c(CCC(=O)O)c(OCCCCCC(<br />=O)O)ccc1
|
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| CAS Number |
CAS 150596-99-9
|
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| PubChem Compound ID | |||||
| Target and Pathway | |||||
| Target(s) | Leukotriene B4 receptor 1 | Target Info | Modulator | [2] | |
| KEGG Pathway | Neuroactive ligand-receptor interaction | ||||
| NetPath Pathway | IL4 Signaling Pathway | ||||
| Reactome | Leukotriene receptors | ||||
| G alpha (q) signalling events | |||||
| WikiPathways | Nucleotide GPCRs | ||||
| GPCRs, Class A Rhodopsin-like | |||||
| Gastrin-CREB signalling pathway via PKC and MAPK | |||||
| Spinal Cord Injury | |||||
| GPCR ligand binding | |||||
| GPCR downstream signaling | |||||
| References | |||||
| REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800005401) | ||||
| REF 2 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800005401) | ||||
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