TTD | Drug: D0Z4GJ

Drug General Information
Drug ID	D0Z4GJ
Former ID	DIB018873
Drug Name	AR-C118925XX
Synonyms	AR-C118925
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[541200]
Structure		Download 2D MOL
Formula	C28H23N7O3S
InChI	InChI=1S/C28H23N7O3S/c1-15-3-8-20-17(11-15)5-6-18-12-16(2)4-9-21(18)24(20)22-14-35(28(37)30-26(22)39)13-19-7-10-23(38-19)25(36)29-27-31-33-34-32-27/h3-12,14,24H,13H2,1-2H3,(H,30,37,39)(H2,29,31,32,33,34,36)
InChIKey	PVKNPGQAFNALOI-UHFFFAOYSA-N
PubChem Compound ID	54210200
PubChem Substance ID	128973789, 178102530, 233412226, 249691328, 249896003, 252158443
Target and Pathway
Target(s)	P2Y purinoceptor 2	Target Info	Antagonist	[527128]
KEGG Pathway	Neuroactive ligand-receptor interaction
KEGG Pathway	Inflammatory mediator regulation of TRP channels
NetPath Pathway	IL5 Signaling Pathway
Reactome	G alpha (q) signalling events
	P2Y receptors
	Surfactant metabolism
WikiPathways	Nucleotide GPCRs
	GPCRs, Class A Rhodopsin-like
	Gastrin-CREB signalling pathway via PKC and MAPK
	GPCR ligand binding
	GPCR downstream signaling
References
Ref 541200	(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 5907).
Ref 527128	Nucleotide-mediated mucin secretion from differentiated human bronchial epithelial cells. Am J Respir Cell Mol Biol. 2004 Oct;31(4):446-55. Epub 2004 Jul 1.

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Drug Information