Drug Information
Drug General Information | |||||
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Drug ID |
D0Z5HR
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Former ID |
DIB009120
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Drug Name |
VX-661
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Synonyms |
CFTR correctors (cystic fibrosis), Vertex; Cystic fibrosis transmembrane regulator corrector (cystic fibrosis), Vertex
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Drug Type |
Small molecular drug
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Indication | Cystic fibrosis [ICD9: 277; ICD10:E84] | Phase 2 | [525275] | ||
Company |
Vertex Pharmaceuticals Inc
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Structure |
Download2D MOL |
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Formula |
C26H27F3N2O6
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Canonical SMILES |
CC(C)(CO)C1=CC2=CC(=C(C=C2N1CC(CO)O)F)NC(=O)C3(CC3)C4=C<br />C5=C(C=C4)OC(O5)(F)F
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InChI |
1S/C26H27F3N2O6/c1-24(2,13-33)22-8-14-7-18(17(27)10-19(14)31(22)11-16(34)12-32)30-23(35)25(5-6-25)15-3-4-20-21(9-15)37-26(28,29)36-20/h3-4,7-10,16,32-34H,5-6,11-13H2,1-2H3,(H,30,35)/t16-/m1/s1
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InChIKey |
MJUVRTYWUMPBTR-MRXNPFEDSA-N
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PubChem Compound ID | |||||
PubChem Substance ID | |||||
Target and Pathway | |||||
Target(s) | cystic fibrosis transmembrane conductance regulator | Target Info | Regulator | [532904] | |
WikiPathways | ABC-family proteins mediated transport | ||||
References |
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