Drug Information
Drug General Information | |||||
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Drug ID |
D0Z6IB
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Former ID |
DIB010021
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Drug Name |
AVP-786
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Indication | Pain [ICD9: 338, 356.0, 356.8,780; ICD10:G64, G90.0, R52, G89] | Phase 1 | [1], [2] | ||
Company |
Avanir pharmaceuticals
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Structure |
Download2D MOL |
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Target and Pathway | |||||
Target(s) | Sodium-dependent serotonin transporter | Target Info | Modulator | [1], [2] | |
Sigma(1)-type opioid receptor | Target Info | Modulator | [1], [2] | ||
KEGG Pathway | Serotonergic synapse | ||||
NetPath Pathway | TCR Signaling Pathway | ||||
PANTHER Pathway | 5HT1 type receptor mediated signaling pathway | ||||
5HT2 type receptor mediated signaling pathway | |||||
5HT3 type receptor mediated signaling pathway | |||||
5HT4 type receptor mediated signaling pathway | |||||
WikiPathways | Monoamine Transport | ||||
SIDS Susceptibility Pathways | |||||
NRF2 pathway | |||||
Synaptic Vesicle Pathway | |||||
Serotonin Transporter ActivityWP2006:miR-targeted genes in squamous cell - TarBase | |||||
miR-targeted genes in lymphocytes - TarBase | |||||
References | |||||
REF 1 | Dextromethorphan antagonizes the acute depletion of brain serotonin by p-chloroamphetamine and H75/12 in rats. Brain Res. 1992 Oct 30;594(2):323-6. | ||||
REF 2 | Antitussives and substance abuse. Subst Abuse Rehabil. 2013 Nov 6;4:75-82. | ||||
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