Drug Information
Drug General Information | |||||
---|---|---|---|---|---|
Drug ID |
D0Z6TG
|
||||
Drug Name |
ZD-6021
|
||||
Synonyms |
ZD-6021; 255049-08-2; ZD-6021
|
||||
Drug Type |
Small molecular drug
|
||||
Indication | Unspecified | Investigative | [1], [2] | ||
Structure |
![]() |
Download2D MOL |
|||
Formula |
C35H35Cl2N3O2S
|
||||
PubChem Compound ID | |||||
Target and Pathway | |||||
Target(s) | Substance-P receptor | Target Info | Modulator | ||
NK-2 receptor | Target Info | Modulator | |||
KEGG Pathway | Calcium signaling pathway | ||||
Neuroactive ligand-receptor interaction | |||||
Measleshsa04020:Calcium signaling pathway | |||||
PANTHER Pathway | CCKR signaling map ST | ||||
Reactome | G alpha (q) signalling eventsR-HSA-416476:G alpha (q) signalling events | ||||
WikiPathways | SIDS Susceptibility Pathways | ||||
Gastrin-CREB signalling pathway via PKC and MAPK | |||||
Spinal Cord Injury | |||||
Peptide GPCRs | |||||
GPCR ligand binding | |||||
GPCR downstream signalingWP2664:Gastrin-CREB signalling pathway via PKC and MAPK | |||||
GPCR downstream signaling | |||||
References | |||||
REF 1 | Molecular cloning, mutations and effects of NK1 receptor antagonists reveal the human-like pharmacology of gerbil NK1 receptors.Biochem Pharmacol.2007 Jan 15;73(2):259-69. | ||||
REF 2 | Pharmacological characterization of ZD6021: a novel, orally active antagonist of the tachykinin receptors. |
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.