Drug Information
Drug General Information | |||||
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Drug ID |
D0Z6UC
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Former ID |
DAP000219
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Drug Name |
Sumatriptan
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Synonyms |
Imigran; Imitrex; Sumatran; Sumatriptanum; Sumax; GR 43175; GR 43175X; NP101; GR-43175; Imigran (TN); Imitrex (TN); KS-1116; Sumatriptanum [INN-Latin]; Sumatriptan (JAN/USP/INN); (3-[2-(Dimethylamino)ethyl]-1H-indol-5-yl)-N-methylmethanesulfonamide; 1-[3-(2-dimethylaminoethyl)-1H-indol-5-yl]-N-methyl-methanesulfonamide; 1-[3-(2-dimethylaminoethyl)-1H-indol-5-yl]-N-methylmethanesulfonamide; 1-{3-[2-(dimethylamino)ethyl]-1H-indol-5-yl}-N-methylmethanesulfonamide; 3-(2-(Dimethylamino)ethyl)-N-methyl-1H-indole-5-methanesulfonamide; 3-[2-(Dimethylamino)ethyl]-N-methyl-1H-indole-5-methanesulfonamide; 3-[2-(Dimethylamino)ethyl]-N-methylindole-5-methanesulfonamide
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Drug Type |
Small molecular drug
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Therapeutic Class |
Vasoconstrictor Agents
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Company |
GlaxoSmithKline
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Structure |
Download2D MOL |
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Formula |
C14H21N3O2S
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InChI |
InChI=1S/C14H21N3O2S/c1-15-20(18,19)10-11-4-5-14-13(8-11)12(9-16-14)6-7-17(2)3/h4-5,8-9,15-16H,6-7,10H2,1-3H3
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InChIKey |
KQKPFRSPSRPDEB-UHFFFAOYSA-N
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CAS Number |
CAS 103628-46-2
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PubChem Compound ID | |||||
PubChem Substance ID |
9527, 5634131, 7847517, 7980713, 8153293, 10502764, 14718471, 14825017, 25819952, 26612933, 26749855, 29224410, 46506520, 48334598, 48416587, 49679316, 49984205, 50107736, 50422744, 53790264, 56322605, 57322735, 81040912, 85209322, 85789242, 93166406, 103188807, 103919260, 104309008, 119526324, 124799677, 125336887, 126525330, 126667002, 128419875, 134337534, 135018088, 135651095, 137002439, 142467611, 144205081, 152034343, 160964014, 162182413, 164814822, 165699400, 170465377, 172866507, 174006309, 175265694
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ChEBI ID |
ChEBI:10650
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SuperDrug ATC ID |
N02CC01
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SuperDrug CAS ID |
cas=103628462
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Target and Pathway | |||||
References | |||||
Ref 536361 | Natural products as sources of new drugs over the last 25 years. J Nat Prod. 2007 Mar;70(3):461-77. Epub 2007 Feb 20. | ||||
Ref 540805 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 54). | ||||
Ref 534894 | 5-Hydroxytryptamine(1F) receptors do not participate in vasoconstriction: lack of vasoconstriction to LY344864, a selective serotonin(1F) receptor agonist in rabbit saphenous vein. J Pharmacol Exp Ther. 1999 Sep;290(3):935-9. | ||||
Ref 534966 | Novel approaches to the treatment of nausea and vomiting. Dig Dis. 1999;17(3):125-32. | ||||
Ref 535146 | Irritable bowel syndrome: new agents targeting serotonin receptor subtypes. Drugs. 2001;61(3):317-32. | ||||
Ref 535803 | 5-Hydroxytryptamine receptor agonists for the abortive treatment of vascular headaches block mast cell, endothelial and platelet activation within the rat dura mater after trigeminal stimulation. Brain Res. 1992 Jun 26;583(1-2):137-49. | ||||
Ref 538154 | Serotonin in migraine: theories, animal models and emerging therapies. Prog Drug Res. 1998;51:219-44. |
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