Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0Z7AN
|
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| Former ID |
DIB008489
|
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| Drug Name |
Ro-19-8022
|
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| Drug Type |
Small molecular drug
|
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| Indication | Anxiety disorder [ICD9: 300, 311; ICD10:F32, F40-F42] | Terminated | [1] | ||
| Company |
Roche Holding AG
|
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| Structure |
|
Download2D MOL |
|||
| Formula |
C25H21ClN2O3
|
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| Canonical SMILES |
c1(c2n(c(=O)c(c1)c1ccccc1)ccc1c2cc(cc1)Cl)C(=O)N1[C@@H]<br />(CO)CCC1
|
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| CAS Number |
CAS 104604-66-2
|
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| PubChem Compound ID | |||||
| Target and Pathway | |||||
| Target(s) | GABA A receptor | Target Info | Modulator | ||
| KEGG Pathway | Neuroactive ligand-receptor interaction | ||||
| Retrograde endocannabinoid signaling | |||||
| GABAergic synapse | |||||
| Morphine addiction | |||||
| Nicotine addiction | |||||
| Reactome | Ligand-gated ion channel transport | ||||
| GABA A receptor activation | |||||
| WikiPathways | SIDS Susceptibility Pathways | ||||
| Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell | |||||
| Iron uptake and transport | |||||
| References | |||||
| REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800001584) | ||||
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