Drug Information

Drug General Information
Drug ID
D0Z7BC
Former ID
DNC010857
Drug Name
VCP-28
Drug Type
Small molecular drug
Indication Discovery agent Investigative [530849]
Structure
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2D MOL

3D MOL
Formula
C19H29N6O5
Canonical SMILES
CC1(CC(C(N1[O])(C)C)CNC2=NC=NC3=C2N=CN3C4C(C(C(O4)CO)O)<br />O)C
InChI
1S/C19H29N6O5/c1-18(2)5-10(19(3,4)25(18)29)6-20-15-12-16(22-8-21-15)24(9-23-12)17-14(28)13(27)11(7-26)30-17/h8-11,13-14,17,26-28H,5-7H2,1-4H3,(H,20,21,22)/t10?,11-,13-,14-,17-/m1/s1
InChIKey
QFFVFNDFHJHEHU-QIFOKDCASA-N
PubChem Compound ID
44442164
Target and Pathway
Target(s) Adenosine A1 receptor Target Info Inhibitor [530849]
KEGG Pathway cGMP-PKG signaling pathway
cAMP signaling pathway
Sphingolipid signaling pathway
Neuroactive ligand-receptor interaction
Morphine addiction
NetPath Pathway TCR Signaling Pathway
RANKL Signaling Pathway
PANTHER Pathway Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway
Reactome Adenosine P1 receptors
G alpha (i) signalling events
WikiPathways Nucleotide GPCRs
GPCRs, Class A Rhodopsin-like
GPCR ligand binding
GPCR downstream signaling
References
Ref 530849Bioorg Med Chem. 2010 May 1;18(9):3078-87. Epub 2010 Mar 27.Synthesis and evaluation of new N6-substituted adenosine-5'-N-methylcarboxamides as A3 adenosine receptor agonists.
Ref 530849Bioorg Med Chem. 2010 May 1;18(9):3078-87. Epub 2010 Mar 27.Synthesis and evaluation of new N6-substituted adenosine-5'-N-methylcarboxamides as A3 adenosine receptor agonists.

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