Drug Information
Drug General Information | |||||
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Drug ID |
D0Z7TM
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Former ID |
DNC008462
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Drug Name |
BMS-645737
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Drug Type |
Small molecular drug
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Indication | Discovery agent | Investigative | [529409] | ||
Structure |
Download2D MOL |
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Formula |
C20H20N8O
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Canonical SMILES |
CC1=CC2=CC(=CN=C2N1)NC3=NC=NN4C3=C(C(=C4)C5=NN=C(O5)C)C<br />(C)C
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InChI |
1S/C20H20N8O/c1-10(2)16-15(20-27-26-12(4)29-20)8-28-17(16)19(22-9-23-28)25-14-6-13-5-11(3)24-18(13)21-7-14/h5-10H,1-4H3,(H,21,24)(H,22,23,25)
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InChIKey |
OOQXPATWSOGSAV-UHFFFAOYSA-N
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PubChem Compound ID | |||||
Target and Pathway | |||||
Target(s) | Vascular endothelial growth factor receptor 2 | Target Info | Inhibitor | [529409] | |
Potassium voltage-gated channel subfamily H member 2 | Target Info | Inhibitor | [529409] | ||
NetPath Pathway | IL2 Signaling Pathway | ||||
PANTHER Pathway | Angiogenesis | ||||
VEGF signaling pathway | |||||
Pathway Interaction Database | HIF-2-alpha transcription factor network | ||||
Beta3 integrin cell surface interactions | |||||
Signaling events mediated by TCPTP | |||||
SHP2 signaling | |||||
S1P1 pathway | |||||
VEGF and VEGFR signaling network | |||||
Integrins in angiogenesis | |||||
Signaling events mediated by VEGFR1 and VEGFR2 | |||||
Notch-mediated HES/HEY network | |||||
PathWhiz Pathway | Muscle/Heart Contraction | ||||
References |
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