Resistance mutation info of target
| Target General Information | ||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Target ID | T53489 | |||||||||||||||||
| Target Name | Parasitic Cytochrome b (MT-CYB) | Target Info | ||||||||||||||||
| Gene Name | MT-CYB | |||||||||||||||||
| Species | Plasmodium falciparum | |||||||||||||||||
| Uniprot ID | CYB_PLAFA | |||||||||||||||||
| Sequence | MNFYSINLVKAHLINYPCPLNINFLWNYGFLLGIIFFIQIITGVFLASRYTPDVSYAYYS IQHILRELWSGWCFRYMHATGASLVFLLTYLHILRGLNYSYMYLPLSWISGLILFMIFIV TAFVGYVLPWGQMSYWGATVITNLLSSIPVAVIWICGGYTVSDPTIKRFFVLHFILPFIG LCIVFIHIFFLHLHGSTNPLGYDTALKIPFYPNLLSLDVKGFNNVIILFLIQSLFGIIPL SHPDNAIVVNTYVTPSQIVPEWYFLPFYAMLKTVPSKPAGLVIVLLSLQLLFLLAEQRSL TTIIQFKMIFGARDYSVPIIWFMCAFYALLWIGCQLPQDIFILYGRLFIVLFFCSGLFVL VHYRRTHYDYSSQANI [Plasmodium falciparum] |
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| Drug Resistance Mutation and Corresponding Drugs | ||||||||||||||||||
| Mutation Info | Missense: Y268S | |||||||||||||||||
| Drugs |
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| Reference | ||||||||||||||||||
| REF 1 | Understanding the mechanism of atovaquone drug resistance in Plasmodium falciparum cytochrome b mutation Y268S using computational methods. PLoS One. 2014 Oct 15;9(10):e110041. doi: 10.1371/journal.pone.0110041. eCollection 2014. | |||||||||||||||||
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